Research & publications

Key topics

  • Analytical tomographic reconstruction
  • Iterative tomographic reconstruction
  • Field-of-view extension in cone-beam CT
  • Metal artifact reduction (MAR)
  • Scatter correction / reduction
  • Dual-energy CT
  • Beam hardening correction
  • ML-based artifact reduction
  • Scanner commissioning & QA
  • Flat panel detector characterisation
  • Geometric / flexmap calibration
  • Embedded acquisition systems
  • Optical tracking & stereotaxis
  • Image registration
  • Localization & tracking
  • Monte Carlo simulation (Geant4 / OpenGATE)
  • Computer-Assisted Surgery (CAS)
  • CT/CBCT-derived 3D modeling & stereolithography
  • Surgical navigation

PhD thesis · cum laude

Development of Technologies for In-Room Image Guidance in Hadron Therapy

Politecnico di Milano · November 2019 - March 2024 · Supervisor: Prof. Guido Baroni

Six chapters on the design, calibration and clinical validation of an in-room imaging system for hadron therapy: from field-of-view extension in cone-beam geometry (nearly doubling the usable radius, from 102 to 181 mm) to breathing-correlated 4D imaging strategies, through to deep learning techniques for artefact reduction in CBCT.

Read the full thesis (PDF, Politesi - Politecnico di Milano)

Journal articles

  • Belotti, G., Fattori, G., Baroni, G., Rit, S. (2024). Extension of the cone-beam CT field-of-view using two complementary short scans. Medical Physics, 51(5), 3391-3404.

    DOI: 10.1002/mp.16869
  • Knausl, B., Belotti, G., et al. (2024). A review of the clinical introduction of 4D particle therapy research concepts. Physics and Imaging in Radiation Oncology, 29, 100535.

    DOI: 10.1016/j.phro.2024.100535
  • Rossi, M., Belotti, G., et al. (2024). Feasibility of proton dosimetry overriding planning CT with daily CBCT elaborated through generative artificial intelligence tools. Computer Assisted Surgery, 29(1), 2327981.

    DOI: 10.1080/24699322.2024.2327981
  • Belotti, G., Rossi, M., Pella, A., Cerveri, P., Baroni, G. (2023). A new system for in-room image guidance in particle therapy at CNAO. Physica Medica, 114, 103162.

    DOI: 10.1016/j.ejmp.2023.103162
  • Antonioli, L., Pella, A., Ricotti, R., Rossi, M., Fiore, M.R., Belotti, G., et al. (2021). Convolutional Neural Networks Cascade for Automatic Pupil and Iris Detection in Ocular Proton Therapy. Sensors, 21(13), 4400.

    DOI: 10.3390/s21134400
  • Rossi, M., Belotti, G., et al. (2021). Image-based shading correction for narrow-FOV truncated pelvic CBCT with deep convolutional neural networks and transfer learning. Medical Physics, 48(11), 7112-7126.

    DOI: 10.1002/mp.15282
  • Ricotti, R., Pella, A., Mirandola, A., Fiore, M.R., Belotti, G., et al. (2021). Dosimetric effect of variable rectum and sigmoid colon filling during carbon ion radiotherapy to sacral chordoma. Physica Medica, 90, 123-133.

    DOI: 10.1016/j.ejmp.2021.09.012

Conference proceedings

  • Belotti, G., Rit, S., Baroni, G. (2022). Extension of the cone-beam CT field-of-view using two short scans with displaced centers of rotation. Seventh International Conference on Image Formation in X-Ray Computed Tomography (XCT22), SPIE, 12304.

    DOI: 10.1117/12.2646384
  • Russo, F.M., Lamminger, L., Belotti, G., Parodi, K., Deutschmann, H., Steininger, P. (2024). Enhancing CBCT image quality using a novel sCT-based shading correction. XXth International Conference on the Use of Computers in Radiation Therapy (ICCR 2024), Lyon, France.

Other contributions

For completeness, earlier academic contributions outside the X-ray imaging field:

  • Skurzok, M., Bazzi, M., Belotti, G., et al. (2019). Low-energy K⁻ hadronic interactions with light nuclei by AMADEUS. JPS Conference Proceedings, 26, 023011.

    DOI: 10.7566/JPSCP.26.023011
  • Skurzok, M., Bazzi, M., Belotti, G., et al. (2020). Low-energy K⁻ nucleon/multi-nucleon interaction studies by AMADEUS. Recent Progress in Few-Body Physics, Springer Proceedings in Physics, 238, 937-941.

    DOI: 10.1007/978-3-030-32357-8_145

Full publication list on Google Scholar and ORCID.